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| First Name: | Rickard | | Last Name: | Sandberg | | Title: | Assistant Professor | | Advanced Degrees: | Ph.D. | | Affiliation: | Karolinska Institutet | | Department: | Department of Cell and Molecular Biology Ludwig Institute for Cancer Research | | Street Address 1: | Karolinska Institutet | | City: | Stockholm | | Zip/Postal Code: | 171 77 | Country/Territory: | Sweden | | Phone: | +46 8 5248 3986 | | Email Address: |  |
Disclosure:
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Bioinformatics/Statistics, Stem cells, Molecular and Cell biology, DNA microarrays
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We are studying global aspects of gene regulation by combining genome-wide experimental and computational techniques to better understand stem cell characteristics and differentiation processes. We aim towards a better understanding of the molecular regulation of gene expression programs by the combined study of gene regulation acting on different levels (e.g. transcriptional and post-transcriptional) using next-generation sequencing techniques. In particular, we are interested in gene expression regulation of differentiation and cell fates during mouse early embryonic development. |
An abundance of ubiquitously expressed genes revealed by tissue transcriptome sequence data
Ramskold D, Wang ET, Burge CB, Sandberg R
PLoS Comput Biol 2009. 5(12): e1000598. doi:10.1371/journal.pcbi.1000598
Alternative Isoform Regulation in Human Tissue Transcriptomes.
*Wang ET, *Sandberg R, Luo S, Khrebtukova I, Zhang L, Mayr C, Kingsmore SF, Schroth GP, Burge CB.
Nature 2008. 27 Nov. 456, 470-476
Proliferating cells express mRNAs with shortened 3' untranslated regions and fewer microRNA target sites
*Sandberg R, *Neilson JR, Sarma, Sharp PA and Burge CB
Science. 2008. 320, 5883, 1643--7
Improved precision and accuracy for microarrays using updated probe set definitions
Rickard Sandberg and Ola Larsson
BMC Bioinformatics. 2007. 8, 48
Comparative microarray analysis
Ola Larsson and Kristian Wennmalm and Rickard Sandberg
Omics. 2006. 10, 3, 381--97
Assessment of tumor characteristic gene expression in cell lines using a tissue similarity index (TSI)
Rickard Sandberg and Ingemar Ernberg
Proc Natl Acad Sci USA. 2005. 102, 6, 2052--7
Regional and strain-specific gene expression mapping in the adult mouse brain
*Sandberg R, *Yasuda R, Pankratz DG, Carter TA, Del Rio JA, Wodicka L, Mayford M, Lockhart DJ and Barlow C
Proc Natl Acad Sci USA. 2000. 97, 20, 11038--43 |
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